Kulathinal Lab High-throughput Journal Club
Tuesdays at 4pm (BioLife 213A)
Kulathinal Lab Population Genetics Journal Club
Wednesdays at 4pm (BioLife 213A)
Department of Biology Seminar
Mondays at 4:00 (BioLife 234)
This semester's special theme: "Ecological Speciation"
Tuesdays 11:30-12:30 (BioLife 237)
Temple Seminars info >
Philly-area Seminars info >
Hansen EB & Kulathinal RJ. 2013. Sex-biased networks and nodes of sexually antagonistic conflict in Drosophila.. International Journal of Evolutionary Biology 2013:545392
Kulathinal RJ & Singh RS. 2012. Sexual system genomics and speciation. In "Rapidly evolving genes and genetic systems" (Eds: Singh, Xu, and Kulathinal), Oxford University Press, London.
Sackton TB, Kulathinal RJ, Bergman CM, Quinlan AR, Dopman EB, Carneiro M, Marth GT, Hartl DL & Clark AG. 2009. Population genomic inferences from sparse high-throughput sequencing of two populations of Drosophila melanogaster. Genome Biol. Evol. 1:439–455
Kulathinal RJ, Stevison LS & Noor MAF. 2009. The genomics of speciation in Drosophila: Diversity, divergence and introgression estimated from low-coverage whole genome shotgun sequences. PLoS Genetics 5:e1000550
Kulathinal RJ, Bennett SM, Fitzpatrick CL & Noor MAF. 2008. Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence. Proceedings of the National Academy of Sciences U.S.A. 105:10051-10056
Kulathinal RJ & Singh RS. 2008. The molecular basis of speciation: From patterns to processes, rules to mechanisms. Journal of Genetics 87:327
Singh RS & Kulathinal RJ. 2005. Male-drive and the masculination of the genome. BioEssays 27:518-525
Kulathinal RJ, Bettencourt BR & Hartl DL. 2004. Compensated deleterious mutations in insect genomes. Science:1553-1554
Our lab is interested in discovering novel evolutionary patterns and processes across a range of data. Our primary focus lies in understanding how variation within species is transformed into the tremendous diversity that is observed among species, a process known as speciation. To address this grand challenge, we employ a combination of experimental, theoretical, and computational approaches that allow us to tease apart the various forces involved in species formation. In particular, we explore genomic landscapes from natural populations of such organisms as fruit flies, butterflies, deep sea corals, apes, and humans to compare selective signatures across different genetic systems. The availability of novel datasets, particularly from new sequencing technologies and initiatives, provides us with an unprecedented number of unexplored landscapes to study the genomics of speciation.
Keywords: evolutionary genetics, population genomics, bioinformatics, speciation theory, reproductive systems, sexual selection
Rob J. Kulathinal, PhD
Ralph Hillman, PhD
Meganathan Ramakodi, PhD
Fox Chase Postdoctoral Fellow
Dr. Kulathinal's Office: BioLife Room 214
Molecular and Fly Laboratory: BioLife Room 213
Computational Laboratory: BioLife Room 213A
(215) 204 0620
Dr. Rob Kulathinal
BioLife Rm 214
1900 N. 12th Street
There are a number of exciting opportunities in the Kulathinal lab for motivated students interested in evolutionary biology, genetics, genomics and/or bioinformatics.
Please send inquiries to: