Kulathinal Lab

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Kulathinal RJ. 2010. Commemorating the 20th century Darwin: Ernst Mayr’s words and thoughts, five years later. Genome 53:157–159

Renn SCP, Machado HE, Jones A, Soneji K, J Kulathinal RJ & Hofmann HA. 2010. Using comparative genomic hybridization to survey genomic sequence divergence across species: a proof-of-concept from Drosophila. BMC Genomics 11:271-282

Sackton TB, Kulathinal RJ, Bergman CM, Quinlan AR, Dopman EB, Carneiro M, Marth GT, Hartl DL & Clark AG. 2009. Population genomic inferences from sparse high-throughput sequencing of two populations of Drosophila melanogaster. Genome Biol. Evol. 1:439–455

Kulathinal RJ, Stevison LS & Noor MAF. 2009. The genomics of speciation in Drosophila: Diversity, divergence and introgression estimated from low-coverage whole genome shotgun sequences. PLoS Genetics 5:e1000550

Shevelyov YY, Lavrov SA, Mikhaylova LM, Nurminsky ID, Kulathinal RJ, Egorova KS, Rozovsky YM & Nurminsky DI. 2009. The B-type lamin is required for somatic repression of testis-specific gene clusters. Proceedings of the National Academy of Sciences U.S.A. 106:3282-3287

Kulathinal RJ, Bennett SM, Fitzpatrick CL & Noor MAF. 2008. Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence. Proceedings of the National Academy of Sciences U.S.A. 105:10051-10056

Kulathinal RJ & Singh RS. 2008. The molecular basis of speciation: From patterns to processes, rules to mechanisms. Journal of Genetics 87:327

Haerty W, Jagadeeshan S, Kulathinal RJ, Wong A, Ravi Ram K, Sirot LK, Levesque L, Artieri CG, Wolfner MF, Civetta A & Singh RS. 2007. Evolution in the fast lane: Rapidly evolving sex-related genes in Drosophila. Genetics 177:1321-1335

Clark AG, Eisen MB, Smith DR,..Kulathinal RJ (one of 417 authors) ...MacCullum I. 2007. Evolution of genes and genomes on the Drosophila phylogeny. Nature 450:203-18

Lin MF, Carlson JW, Crosby MA, Matthews BB, Yu C, Park S, Wan KH, Schroeder AJ, Gramates LS, St Pierre SE, Roark M, Wiley KL Jr, Kulathinal RJ, Zhang P, Myrick KV, Antone JV, Celniker SE, Gelbart WM & Kellis M. 2007. Revisiting the protein-coding gene catalog of Drosophila melanogaster using 12 fly genomes. Genome Research 17:1823-1836

Kulathinal RJ & Hartl DL. 2005. The latest buzz in comparative genomics. Genome Biology 6:201-204 "

Singh RS & Kulathinal RJ. 2005. Male-drive and the masculination of the genome. BioEssays 27:518-525

Kulathinal RJ, Bettencourt BR & Hartl DL. 2004. Compensated deleterious mutations in insect genomes. Science 306:1553-1554

Castillo-Davis CI, Kondrashov FA, Hartl DL & Kulathinal RJ. 2004. The functional genomic distribution of protein divergence in two animal phyla: Co-evolution, genomic conflict, and constraint. Genome Research 14:802-811

Kulathinal RJ & Singh RS. 2004. The nature of genetic variation in sex and reproduction related genes between the sibling species, of the Drosophila melanogaster complex. Genetica 120:245-252

Kulathinal RJ, Skwarek L, Morton RA & Singh RS. 2003. Rapid evolution of the sex determining gene, transformer: Structural diversity and rate heterogeneity among sibling species of Drosophila. Molecular Biology and Evolution 20:441-452

Sawyer SA, Kulathinal RJ, Bustamante CD & Hartl DL. 2003. Bayesian analysis suggests that most amino acid replacements in Drosophila are driven by positive selection. Journal of Molecular Evolution 57:154-164

Kulathinal RJ, Sawyer SA, Bustamante CD, Nurminsky DI, Ponce R, Ranz JM & Hartl DL. 2003. Selective sweep in the evolution of a new sperm-specific gene in Drosophila. In Selective Sweeps, Ed: Dimitry Nurminsky, Kluwer Academic/Plenum Publishers

Torgerson DG, Kulathinal RJ & Singh RS. 2002. Mammalian sperm proteins are rapidly evolving: Evidence of positive selection in functionally diverse genes. Molecular Biology and Evolution 19:1973-1980

Kulathinal RJ & Singh RS. 2000. Reinforcement with gene flow? Evolution 54:2176-2177

Singh RS & Kulathinal RJ. 2000. Sex gene pool evolution and speciation: A new paradigm. Genes & Genetic Systems 75:119-130

Kulathinal RJ & Singh RS. 2000. A biogeographical genetic approach for testing the role of reinforcement: The case of Drosophila pseudoobscura and D. persimilis. Evolution 54:210-217

Kulathinal RJ & Singh RS. 1998. Cytological characterization of premeiotic vs. postmeiotic defects producing hybrid male sterility among sibling species of the Drosophila melanogaster complex. Evolution 52:1067-1079